Mesothelioma Cell Types – Epithelial Mesothelioma
Epithelial mesothelioma has a defined structure, with nuclei visible. This is the most common variant of this type of mesothelioma cancer, representing about 60 percent of cases. This type of mesothelioma develops when malignant cells develop in any of the mesothelial lining. When examined under a microscope, these cell types of mesothelioma are of uniform size and shape, and resemble normal, healthy cells.
Epithelial cells also have a strong resemblance to adenocarcinoma cells, which are also associated with lung tissue. Patients who were diagnosed with adenocarcinoma should also be examined for the diagnosis of mesothelioma as well.
Epithelial Mesothelioma Variants
Papillary mesothelioma is an example of epithelial mesothelioma, other variants include one of the following:
- Signet ring
• Single File
• Adenoid cystic
• Proximity – NOS
• Small Cell
• In Situ
• Positive mucin
• Well-differentiated papillary
• Gaucher Cell-Like
What differentiates these types are the shape, size and formation of cells. This may determine the course of mesothelioma treatment is suitable for situations of the patient.
Epithelial mesothelioma and asbestos
Once the asbestos fibers are inhaled, they lodge in the lung tissue and remain there indefinitely. Mesothelioma is associated with hard, crystalline amphibole asbestos, which is rigid, needle-like fibers that literally put through the lung tissue over time, causing chronic inflammation that ultimately results in malignancy. The latency period of mesothelioma can be anywhere from 5-75 years. Mesothelioma symptoms are similar to other respiratory diseases, which is why the diagnosis of mesothelioma has historically been so difficult to do.