Mesothelioma Cell Types – Sarcomatoid Mesothelioma

Mesothelioma Cell Types – Sarcomatoid Mesothelioma

Sarcomatoid Mesothelioma is a cancer that attacks the lining layer of lubricant inside the chest and abdomen and internal organs. Pathologists categorize cases of mesothelioma cancer according to levels of criteria, which are:


  • Lungs (pleural mesothelioma)
    • Abdomen (peritoneal mesothelioma)
    • Heart (pericardial mesothelioma)


  • Stage 1 mesothelioma – cancer cells began to form
    • Stage 2 mesothelioma – cancer has spread to local
    • Stage 3 mesothelioma – cancer has spread to adjacent areas
    • Stage 4 mesothelioma – cancer metastasis began

Cell structure:

  • epithelial (organized and structured)
    • sarcomatoid (random and irregular)
    biphasic (mixed epithelial and sarcomatoid)
    • Desoplastic (a variant of sarcomatoid variety)

cellular structure is determined by a visual examination of the actual cells under a microscope.

Sarcomatoid Mesothelioma
Sarcomatoid Mesothelioma

About Sarcomatoid Mesothelioma

sarcomatoid mesothelioma accounts for about 10-15 percent of all diagnoses. The types of mesothelioma cells in this case are elongated and spindle-shaped and are arranged in a somewhat disorderly. sarcomatoid cells also lack a nucleus, unlike the epithelioid cells that have nuclei clearly visible.

The variety of desoplastic sarcomatoid mesothelioma is difficult to distinguish healthy tissue, in many cases, making a diagnosis of mesothelioma needs challenging.


Once symptoms of mesothelioma had been cataloged and a history of asbestos exposure determined, the next step is to look inside the body – initially with X-rays, followed by a more sophisticated imaging such as CT or MRI. If these images reveal serious deficiencies, a biopsy (tissue sample) will be ordered. These are examined and analyzed in a laboratory, which usually confirms or contradicts the diagnosis.

When it comes to sarcomatoid mesothelioma, traditional methods of biopsy pose additional challenges, the normal core needle “method often results in false information, such as sarcomatoid cells are often similar in appearance to benign fibrous tissue. In addition, histological methods of diagnosis often makes it difficult to distinguish between sarcomatoid mesothelioma and other cancers unrelated sarcomatoid.

A precise and accurate diagnosis is essential because a wrong diagnosis can lead to an inappropriate course of mesothelioma treatment is prescribed, it is a good idea to get a second opinion and even a third if mesothelioma is suspected.

Treatment Options

While details will differ depending on the case, all forms of cancer are treated through a combination of surgery, radiotherapy and chemotherapy. How these are managed depends on the location and stage of cancer.

Unfortunately, sarcomatoid mesothelioma is notoriously resistant to treatment, and prognosis of mesothelioma is not good. The median survival of mesothelioma between diagnosis and death is seven months.

Malignant Sarcomatoid Mesothelioma

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