Possible New Protein Break Through For Mesothelioma
Possible New Protein Break Through For Mesothelioma, University of Maryland Medical Center say protein essential for mesothelioma growth can be completely inhibited. H. Richard Alexander, Jr, M.D. has been working with his colleagues at University of Maryland Medical Center to identify the role that protein appears to be playing in the growth of mesothelioma.
In particular, Alexander has been concentrating on abdominal mesothelioma (Peritoneal Mesothelioma) which until now has had no real effective treatment.
They have been developing strategies that combine the use of surgery and medicines, such as chemotherapy, whereby they aim to remove as much of the mesothelioma tumour as possible and then follow up with the medicines. This process has worked very well for some patients, but they had noticed that it hadn’t been quite as effective for all sufferers of the very rare disease that kills several hundreds of people in the US each year.
Over the years they have collected and studied the tumours that were removed during the surgical procedures, and studied them very carefully and closely using highly sophisticated molecular techniques. Enabling them to get in much closer than a microscope in a lab, the team made the discovery that proteins are present in high numbers where abdominal mesothelioma is also present, and that these proteins are in fact essential for the growth of the cancer.
They have said that they already have at their disposal, compounds that can “completely inhibit the function of the proteins to which the mesothelioma appears to be addicted”.
What is also encouraging is that they have also discovered that the protein is abundant in many other forms of cancer and so this breakthrough for mesothelioma could indeed lead to further breakthroughs for cancer itself. Good Luck